Fact check: Andy Huang (@that_hugeasian_guy) posted his top 3 peptides of 2025 on Instagram.
Verdict: mixed — Trust Score 55/100
This post is a mix of legitimate scientific interest and misleading marketing. While Retatrutide is a real drug showing significant promise in clinical trials, the post exaggerates its results and pairs it with GHK-Cu and MOTS-c, for which 'longevity' and 'instant' results are not clinically proven in humans. Furthermore, the post encourages the purchase of these substances for human use via an affiliate code, despite labeling them 'for research use only' to bypass FDA regulations.
- Platform
- Source author
- that_hugeasian_guy — see all fact-checks of this account
- Original post
- https://www.instagram.com/p/DSp7j-QD8yz/?igsh=MTc4MmM1YmI2Ng==
- Verified on
- April 14, 2026
- Verification ID
- N6O5f3mRl-aQchNRsJN03Q
Original content reviewed
Platform: INSTAGRAM Author: @that_hugeasian_guy --- Caption/Description --- From everything I’ve tried, read, seen, and talked to others about…these are my top 3 peptides of 2025. What do you think? Which would you replace and with what? This post is for research use only, this is not medical advice. Please consult a qualified doctor or physician when it comes to your health. @xfactor.labs Code- Andy --- Carousel/Slides (5 items) --- Slide 1 (image): Text: ANDY HUANG MY TOP 3 PEPTIDES OF 2025 01 ▶ Slide 2 (image): Text: #1 S-TIER RETATR*TIDE RETA is an amazing weight loss peptide and in my opinion best bang for your buck peptide. It dramatically improves appetite control, insulin sensitivity, and fat loss while reducing inflammation and visceral fat, allowing anyone to become significantly leaner. Phase 3 trial showed patients losing up to 28% of their body weight in 9 months. It also reduced cardiovascular risk markers like non-HDL cholesterol and blood pressure. 02 Slide 3 (image): Text: #2 GHK-CU GHK-CU IS THE BEST AESTHETICS PEPTIDE, EQUALLY POPULAR AMONGST MEN AND WOMEN. IT IMPROVES COLLAGEN PRODUCTION, SKIN QUALITY, WOUND HEALING, HAIR HEALTH, AND TISSUE REPAIR. YOU CAN ACTUALLY SEE RESULTS WITHIN A MATTER OF DAYS. THIS PEPTIDE CAN INCREASE ELASTIN AND COLLAGEN PRODUCTION LEADING TO TIGHTER AND HEALTHIER LOOKING SKIN. GHK-CU DELIVERS VISIBLE COSMETIC UPGRADES AND SYSTEMIC HEALING EFFECTS THUS BECOMING THE NUMBER ONE CHOICE FOR SKIN AND LONGEVITY 03 Slide 4 (image): Text: #3 Mots-c Mots-c improves mitochondrial function, enhances fat oxidation, and increases metabolic flexibility, meaning the body becomes better at switching between carbs and fats for fuel. You get consistently high energy, better endurance, easier fat loss, and no crashes. Everything runs smoother. Better cellular energy and insulin sensitivity leads to more fat loss and longevity. Mots-c changes your body from the inside out 04 Slide 5 (image): Text
Claims analyzed (4)
- verified: Andy Huang (@that_hugeasian_guy) posted his top 3 peptides of 2025 on Instagram.
The metadata and account handle confirm this is an authentic post from the specified user on December 24, 2025. - mostly true: Retatrutide Phase 3 trial showed patients losing up to 28% of their body weight in 9 months.
Phase 2 data published in NEJM showed 24.2% weight loss at 48 weeks. While some Phase 3 'Triumph' trial projections or specific cohorts may approach 28%, the 24% figure is the established clinical benchmark. The 9-month (36-week) timeline is slightly accelerated vs. the 48-week primary endpoints. - misleading: GHK-Cu results can be seen within a matter of days.
Biological processes such as collagen and elastin synthesis, which GHK-Cu promotes, typically take 4 to 12 weeks to manifest visible changes in skin texture or hair growth. 'Days' is a sensationalized marketing claim. - unverifiable: MOTS-c improves mitochondrial function and leads to longevity.
While MOTS-c shows promise in regulating metabolism and extending lifespan in mice, there is currently insufficient clinical evidence from human trials to support 'longevity' claims in humans.
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